The federal government has a central role to play in reversing the legacy of racial segregation and disinvestment that disproportionately harms low-income communities of color. Developed in a partnership between Urban Institute and PolicyLink, this blueprint aims to help federal agency officials, congressional staff, and policy advocates design a next generation of place-based policies and programs that catalyze lasting improvements for the benefit of current and future residents. It responds to the priorities of local practitioners to actively address racial inequity and injustice, bridge sectors and policy domains, respect and build community voice and power, deliver sufficient resources and lasting system reforms, and promote continuous learning. The guidelines offered here apply lessons from past programs and reflect input from a policy working group made up of civic leaders working in communities across the country.